Cell Culture Market

Updated on : June 18, 2023

The global cell culture market in terms of revenue was estimated to be worth $27.9 billion in 2023 and is poised to reach $51.3 billion by 2028, growing at a CAGR of 12.9% from 2023 to 2028. The new research study consists of an industry trend analysis of the market. The new research study consists of industry trends, pricing analysis, patent analysis, conference and webinar materials, key stakeholders, and buying behaviour in the market. The growth of this market is majorly driven by government support and funding for cell-based research and emerging cell culture technologies for cell-based vaccines. Further, the demand for 3D over 2D cell cultures is creating opportunities the growth of this market.

Attractive Opportunities in the Cell Culture Market

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Cell Culture Market Dynamics

DRIVER: Adoption of single-use technologies

Over the last few years, biopharmaceutical manufacturers have increasingly adopted single-use technologies (SUTs). These SUTs have helped comply with stringent regulations and control costs through multiple benefits. Some single-use bioreactors (SUBs) have low operating volume requirements; this allows for more flexibility in production volumes scaled up over time, depending on the demand. Also, SUTs reduce cross-contamination risk, facilitating rapid changeovers and multiple production batches. SUTs also require less space than multiple-use bioreactors, less capital investment, and less sterilization for storage. This reduces the overall operating and maintenance costs and the environmental impact of these operations. The advantages of SUTs have fueled their adoption in the biopharmaceutical sector, thus driving the growth of the overall cell culture industry during the forecast period.

RESTRAINT: Limitations in producing high-density cell cultures

Although the adoption of advanced technologies such as microcarriers is increasing in high-density cell cultures, there are several limitations associated with their use, which makes the process of cell culture very laborious and expensive. Some of them are: Agitation is required in a stirred-tank bioreactor to make a homogenous cell culture system. Fluid turbulence damages cells and results in cell debris formation and low cell yield, thus increasing downstream processing costs. The number of microcarriers needs to be increased for higher culture density. This, however, leads to a higher degree of collisions (bead-to-bead or microcarrier-bound-cells to mechanical impeller), resulting in cell death and decreased cell yield.

OPPORTUNITY: Growth hotspots in emerging economies

Developing countries such as China, India, and other countries in the Asia Pacific are expected to offer significant growth opportunities for players operating in the cell culture industry. The booming biopharmaceutical sector in these countries, increased risk of pandemics (such as swine flu and COVID-19), less-stringent regulatory guidelines, and the low manufacturing cost advantage are the major factors attracting market players to set up and expand their presence in these countries.

CHALLENGE: Disposal of plastic consumables

Cell culture relies heavily on plastic consumables, resulting in the generation of large amounts of plastic waste each year. This has had a negative impact on the environment. However, there are still serious concerns about the disposal of solid waste materials generated by this alternative technology. The majority of single-use bioprocessing systems are constructed of multiple materials or layers, such as polyethylene (PE), polypropylene (PP), ethylene vinyl alcohol, or nylon. Recycling is not an option for such products because separating the components into homogeneous components requires significant effort. As a result, the majority of single-use systems and their components are unsuitable for recycling.

The sera, media, and Rreagents subsegment of the consumables segment dominated cell culture industry

Based on consumables, the cell culture market is segmented into sera, media, & reagents, vessels, and accessories. Cell cultures are used in laboratories for various applications, such as biopharmaceutical production, vaccine production, toxicology, and drug discovery. Sera, media, and reagents are an integral part of cell culture experiments and help in yielding better results. These products are required for cell culturing and expansion. Increasing government initiatives for enhancing cell-based research and investments by companies to develop advanced products are contributing to the growth of the overall market, which in turn is driving the demand for consumables, including sera, media, and reagents.

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Asia Pacific region of cell culture industry, is estimated to register the highest CAGR during the forecast period.

The Asia Pacific region of the cell culture market is estimated to register the highest CAGR during the forecast period. Government initiatives for research on stem cell therapy, the growing geriatric population, the rising prominence of regenerative medicine research, the increasing number of researchers in Japan, the growth of preclinical/clinical research in China, favorable changes in foreign direct investment (FDI) regulations in the pharmaceutical industry in India, and growth of the pharmaceutical & biopharmaceutical sectors in South Korea are the major factors contributing to the growth of the cell culture industry in the Asia Pacific.

Key players in the Cell Culture Market include Thermo Fisher Scientific Inc. (US), Merck KGaA (Germany), Danaher Corporation (US), Sartorius AG (Germany), Corning Incorporated (US).

Scope of the Cell Culture Industry

This report categorizes the cell culture market to forecast revenue and analyze trends in each of the following submarkets:

By Product

• Consumables
• Equipment

By Consumables

• Sera, Media, and Reagents
  • Media (serum-free media, classical media & salts, stem cell culture media, specialty media, chemically defined media, and other media)
  • Sera (fetal bovine sera (FBS), adult bovine sera (ABS), and other animal sera)
  • Reagents (growth factors, supplements, buffers & chemicals, cell dissociation reagents, balanced salt solutions, attachment & matrix factors, antibiotics/antimycotics, contamination detection kits, cryoprotective reagents, and other cell culture reagents)
• Vessels
  • Roller/roux bottles
  • Cell factory systems/cell stacks
  • Multiwell plates
  • Flasks
  • Petri dishes
• Accessories

By Equipment

• Supporting Equipment (filtration systems, cell counters, carbon dioxide incubators, centrifuges, autoclaves, microscopes, biosafety cabinets, other supporting equipment)
• Bioreactors (conventional bioreactors, single-use bioreactors)
• Storage Equipment (Refrigerators & freezers, Cryostorage systems)

By Application

• Biopharmaceutical Production
  • Monoclonal antibodies
  • Vaccines production
  • Other therapeutic proteins
• Diagnostics
• Drug Screening & Development
• Tissue Engineering & Regenerative Medicine
  • Cell and gene therapy
  • Other tissue engineering & regenerative medicine applications
• Other Applications

By End user

• Pharmaceutical & Biotechnology Companies
• Hospitals & Diagnostic Laboratories
• Research & Academic Institutes
• Other End Users

By Region

• North America
  • US
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Rest of Europe (RoE)
• Asia Pacific (APAC)
  • China
  • Japan
  • India
  • South Korea
  • Rest of Asia Pacific (RoAPAC)
• Latin America (LATAM)
  • Brazil
  • Mexico
  • RoLATAM
• Middle East and Africa (MEA)

Recent Developments of Cell Culture Industry

• In February 2022, Thermo Fisher Scientific announced a 15-year strategic collaboration agreement to enable dedicated large-scale manufacturing in the US.
• In October 2022, Cytiva acquired Cevec Pharmaceuticals GmbH, which is expected to strengthen Cytiva’s leading position in biomanufacturing solutions.

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